Integrins in Hypertensive Remodeling
نویسندگان
چکیده
منابع مشابه
Integrins in hypertensive remodeling.
As nurse Abby in the popular television series “E.R.” well knew (http://www.erheadquarters.com/episodes/ 10/10204.htm), the law of Laplace states that wall stress equals pressure times radius divided by wall thickness. This law leaves 2 options for a vessel to normalize its wall stress in hypertension: either reorganize the available material around a smaller lumen or undergo hypertrophy. In va...
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At the level of the resistance artery, hypertension also brings about a thickening of the vascular wall and inward encroachment on the lumen. This has been reported as being attributable to hypertrophy or hyperplasia of vascular smooth muscle cells (VSMCs), but studies have appeared suggesting that growth is not apparent in arteries at this level of the circulation.1 In addition, detailed struc...
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everal decades ago, the severity of heart failure was gauged ccording to a depression in myocardial contractility, dened as that biochemical property of cardiac muscle that etermines the extent of shortening independent of its nitial length and the load against which it shortens. athematical models were used to derive indices of conractility (1). These theoretical constructs included a conracti...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2005
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.0000198540.38872.47